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Type IV collagen reduces mucin 5AC secretion in three-dimensional cultured human primary airway epithelial cells

Mucin 5AC (MUC5AC) hypersecretion induces airway narrowing in patients with asthma, which leads to breathing problems. We investigated the regulation of MUC5AC secretion by extracellular matrix (ECM) proteins in human primary airway epithelial cells from patients with asthma. The addition of type IV...

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Detalles Bibliográficos
Autores principales: Ito, Yuho, Iwashita, Jun, Murata, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849133/
https://www.ncbi.nlm.nih.gov/pubmed/31737795
http://dx.doi.org/10.1016/j.bbrep.2019.100707