Identification of plicamycin, TG02, panobinostat, lestaurtinib, and GDC-0084 as promising compounds for the treatment of central nervous system infections caused by the free-living amebae Naegleria, Acanthamoeba and Balamuthia

The free-living amebae Naegleria, Acanthamoeba, and Balamuthia cause rare but life-threatening infections. All three parasites can cause meningoencephalitis. Acanthamoeba can also cause chronic keratitis and both Balamuthia and Acanthamoeba can cause skin and systemic infections. There are minimal d...

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Detalles Bibliográficos
Autores principales: Kangussu-Marcolino, Monica M., Ehrenkaufer, Gretchen M., Chen, Emily, Debnath, Anjan, Singh, Upinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849155/
https://www.ncbi.nlm.nih.gov/pubmed/31707263
http://dx.doi.org/10.1016/j.ijpddr.2019.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849155/
https://www.ncbi.nlm.nih.gov/pubmed/31707263
http://dx.doi.org/10.1016/j.ijpddr.2019.10.003

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