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Tim-3 signaling blockade with α-lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA-infected mice

BACKGROUND: Malaria, one of the largest health burdens worldwide, is caused by Plasmodium spp. infection. Upon infection, the host’s immune system begins to clear the parasites. However, Plasmodium species have evolved to escape the host’s immune clearance. T-cell immunoglobulin and mucin domain 3 (...

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Detalles Bibliográficos
Autores principales: Zhang, Yiwei, Jiang, Ning, Zhang, Ting, Chen, Ran, Feng, Ying, Sang, Xiaoyu, Yang, Na, Chen, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849286/
https://www.ncbi.nlm.nih.gov/pubmed/31711531
http://dx.doi.org/10.1186/s13071-019-3788-x