Advances and perspectives of PARP inhibitors

DNA damage repair deficiency leads to the increased risk of genome instability and oncogenic transformation. In the meanwhile, this deficiency could be exploited for cancer treatment by inducing excessive genome instability and catastrophic DNA damage. Continuous DNA replication in cancer cells lead...

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Detalles Bibliográficos
Autores principales: Yi, Ming, Dong, Bing, Qin, Shuang, Chu, Qian, Wu, Kongming, Luo, Suxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849303/
https://www.ncbi.nlm.nih.gov/pubmed/31737426
http://dx.doi.org/10.1186/s40164-019-0154-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849303/
https://www.ncbi.nlm.nih.gov/pubmed/31737426
http://dx.doi.org/10.1186/s40164-019-0154-9

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