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Enantioselective Copper-Catalyzed Cyanation of Remote C(sp(3))-H Bonds Enabled by 1,5-Hydrogen Atom Transfer

The direct functionalization of C(sp(3))-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion. Nevertheless, achieving high levels of chemo-, regio-, and enantioselectivity in these reactions remains challenging...

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Detalles Bibliográficos
Autores principales: Wang, Cheng-Yu, Qin, Zi-Yang, Huang, Yu-Ling, Jin, Ruo-Xing, Lan, Quan, Wang, Xi-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849353/
https://www.ncbi.nlm.nih.gov/pubmed/31707261
http://dx.doi.org/10.1016/j.isci.2019.10.048