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Enantioselective Copper-Catalyzed Cyanation of Remote C(sp(3))-H Bonds Enabled by 1,5-Hydrogen Atom Transfer
The direct functionalization of C(sp(3))-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion. Nevertheless, achieving high levels of chemo-, regio-, and enantioselectivity in these reactions remains challenging...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849353/ https://www.ncbi.nlm.nih.gov/pubmed/31707261 http://dx.doi.org/10.1016/j.isci.2019.10.048 |