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Targeted Drug-Loaded Chemical Probe Staining Assay to Predict Therapy Response and Function as an Independent Pathological Marker

Multi-targeted kinase inhibitors, such as sorafenib, have been used in various malignancies, but their efficacy in clinical applications varies among individuals and lacks pretherapeutic prediction measures. We applied the concept of “click chemistry” to pathological staining and established a drug-...

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Detalles Bibliográficos
Autores principales: Zhang, Heng, Zhong, Wei-long, Sun, Bo, Yang, Guang, Liu, Yan-rong, Zhou, Bi-jiao, Chen, Xin, Jing, Xiang-yan, Huai, Long-cong, Liu, Ning, Zhang, Zhi-yuan, Li, Mi-mi, Han, Jing-xia, Qiao, Kai-liang, Meng, Jing, Zhou, Hong-gang, Chen, Shuang, Yang, Cheng, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849364/
https://www.ncbi.nlm.nih.gov/pubmed/31715498
http://dx.doi.org/10.1016/j.isci.2019.10.050