Synthesis of γ-substituted carbonyl compounds from DMSO-mediated oxidation of enynamides: mechanistic insights and carbon- and hetero-functionalizations

Oxidative coupling of 1,3-enynamides using DMSO as a terminal oxidant has been developed. Carbon as well as unmodified heteroatom nucleophiles, including aliphatic alcohols, thiols, and hydrazides, could be efficiently alkylated at the γ-position in a highly regioselective fashion. The kinetic analy...

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Detalles Bibliográficos
Autores principales: Nguyen, Quynh H., Nguyen, Nguyen H., Kim, Hanbyul, Shin, Seunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849631/
https://www.ncbi.nlm.nih.gov/pubmed/31803452
http://dx.doi.org/10.1039/c9sc03663f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849631/
https://www.ncbi.nlm.nih.gov/pubmed/31803452
http://dx.doi.org/10.1039/c9sc03663f

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