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Selective single C–F bond arylation of trifluoromethylalkene derivatives
A strategically novel single C–F bond functionalization of CF(3)-derived molecules, which shows a prominent advantage for the expedient construction of difluoromethylene-bridged organic scaffolds, is disclosed. The reported protocol consists of S(N)2′ amination, N-alkylation and palladium-catalyzed...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849639/ https://www.ncbi.nlm.nih.gov/pubmed/31803445 http://dx.doi.org/10.1039/c9sc01966a |