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Death receptor 5 is activated by fucosylation in colon cancer cells

The remarkable pro‐apoptotic properties of tumour necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) have led to considerable interest in this protein as a potential anticancer therapeutic. However, TRAIL is largely ineffective in inducing apoptosis in certain cancer cells, and the mech...

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Detalles Bibliográficos
Autores principales: Zhang, Baojie, van Roosmalen, Ingrid A. M., Reis, Carlos R., Setroikromo, Rita, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849799/
https://www.ncbi.nlm.nih.gov/pubmed/30589515
http://dx.doi.org/10.1111/febs.14742