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Control and regulation of S‐Adenosylmethionine biosynthesis by the regulatory β subunit and quinolone‐based compounds

Methylation is an underpinning process of life and provides control for biological processes such as DNA synthesis, cell growth, and apoptosis. Methionine adenosyltransferases (MAT) produce the cellular methyl donor, S‐Adenosylmethionine (SAMe). Dysregulation of SAMe level is a relevant event in man...

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Detalles Bibliográficos
Autores principales: Panmanee, Jiraporn, Bradley‐Clarke, Jack, Mato, Jose M., O'Neill, Paul M., Antonyuk, Svetlana V., Hasnain, S. Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850014/
https://www.ncbi.nlm.nih.gov/pubmed/30776190
http://dx.doi.org/10.1111/febs.14790