Cargando…

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β

BACKGROUND: Atopic dermatitis (AD) is one of the most common skin diseases with a multifactorial etiology. Mutations leading to loss of skin barrier function are associated with the development of AD with group 2 innate lymphoid cells (ILC2) promoting acute skin inflammation. Filaggrin‐mutant (Flg(f...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwartz, Christian, Moran, Tara, Saunders, Sean P., Kaszlikowska, Agnieszka, Floudas, Achilleas, Bom, Joana, Nunez, Gabriel, Iwakura, Yoichiro, O’Neill, Luke, Irvine, Alan D., McKenzie, Andrew N. J., Ogg, Graham, Walsh, Patrick T., Demengeot, Jocelyne, Fallon, Padraic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850072/
https://www.ncbi.nlm.nih.gov/pubmed/30937919
http://dx.doi.org/10.1111/all.13801