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Inhibition of autotransporter biogenesis by small molecules

Disarming pathogens by targeting virulence factors is a promising alternative to classic antibiotics. Many virulence factors in Gram‐negative bacteria are secreted via the autotransporter (AT) pathway, also known as Type 5 secretion. These factors are secreted with the assistance of two membrane‐bas...

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Detalles Bibliográficos
Autores principales: Steenhuis, Maurice, Abdallah, Abdallah M., de Munnik, Sabrina M., Kuhne, Sebastiaan, Sterk, Geert‐Jan, van den Berg van Saparoea, Bart, Westerhausen, Sibel, Wagner, Samuel, van der Wel, Nicole N., Wijtmans, Maikel, van Ulsen, Peter, Jong, Wouter S. P., Luirink, Joen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850105/
https://www.ncbi.nlm.nih.gov/pubmed/30983025
http://dx.doi.org/10.1111/mmi.14255