Molecular model linking Th2 polarized M2 tumour‐associated macrophages with deaminase‐mediated cancer progression mutation signatures

A new and diverse range of somatic mutation signatures are observed in late‐stage cancers, but the underlying reasons are not fully understood. We advance a “combinatorial association model” for deaminase binding domain (DBD) diversification to explain the generation of previously observed cancer‐pr...

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Detalles Bibliográficos
Autores principales: Mamrot, Jared, Balachandran, Siddharth, Steele, Edward J., Lindley, Robyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Discussion Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850162/
https://www.ncbi.nlm.nih.gov/pubmed/30802996
http://dx.doi.org/10.1111/sji.12760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850162/
https://www.ncbi.nlm.nih.gov/pubmed/30802996
http://dx.doi.org/10.1111/sji.12760

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