Oxidized low‐density lipoprotein promotes vascular endothelial cell dysfunction by stimulating miR‐496 expression and inhibiting the Hippo pathway effector YAP

Oxidized low‐density lipoprotein (ox‐LDL) can damage vascular endothelial cells and cause atherosclerosis, but its epigenetic regulatory mechanism has not been fully elucidated. We show that ox‐LDL induced significant apoptosis and loss of function in human umbilical vascular endothelial cells (HUVE...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Jun, Liu, Te, Zhang, Zhuang, Xu, Yawei, Zhu, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850352/
https://www.ncbi.nlm.nih.gov/pubmed/30811087
http://dx.doi.org/10.1002/cbin.11120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850352/
https://www.ncbi.nlm.nih.gov/pubmed/30811087
http://dx.doi.org/10.1002/cbin.11120

Ejemplares similares