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Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

Understanding the mechanisms that promote the specification of pancreas progenitors and regulate their self‐renewal and differentiation will help to maintain and expand pancreas progenitor cells derived from human pluripotent stem (hPS) cells. This will improve the efficiency of current differentiat...

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Detalles Bibliográficos
Autores principales: Giannios, Ioannis, Serafimidis, Ioannis, Anastasiou, Vivian, Pezzolla, Daniela, Lesche, Mathias, Andree, Cordula, Bickle, Marc, Gavalas, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850398/
https://www.ncbi.nlm.nih.gov/pubmed/30681750
http://dx.doi.org/10.1002/stem.2979