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Effects of 6-mercaptopurine in pressure overload induced right heart failure

BACKGROUND: Several antineoplastic drugs have been proposed as new compounds for pulmonary arterial hypertension treatment but many have cardiotoxic side effects. The chemotherapeutic agent 6-mercaptopurine may have an effect in treatment of pulmonary arterial hypertension but at the same time, its...

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Detalles Bibliográficos
Autores principales: Axelsen, Julie Birkmose, Andersen, Stine, Sun, Xiao-Qing, Ringgaard, Steffen, Hyldebrandt, Janus Adler, Kurakula, Kondababu, Goumans, Marie-José, de Man, Frances S., Nielsen-Kudsk, Jens Erik, Bogaard, Harm-Jan, Andersen, Asger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850541/
https://www.ncbi.nlm.nih.gov/pubmed/31714926
http://dx.doi.org/10.1371/journal.pone.0225122