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Sodium butyrate attenuates angiotensin II‐induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6‐dependent mechanism

Sodium butyrate (NaBu) is reported to play important roles in a number of chronic diseases. The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)‐induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models. Sprague Dawley rats were infused...

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Detalles Bibliográficos
Autores principales: Zhang, Linlin, Deng, Mokan, Lu, Aihua, Chen, Yanting, Chen, Yang, Wu, Chunying, Tan, Zhi, Boini, Krishna M., Yang, Tianxin, Zhu, Qing, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850921/
https://www.ncbi.nlm.nih.gov/pubmed/31565858
http://dx.doi.org/10.1111/jcmm.14684