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Sodium butyrate attenuates angiotensin II‐induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6‐dependent mechanism
Sodium butyrate (NaBu) is reported to play important roles in a number of chronic diseases. The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)‐induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models. Sprague Dawley rats were infused...
Autores principales: | Zhang, Linlin, Deng, Mokan, Lu, Aihua, Chen, Yanting, Chen, Yang, Wu, Chunying, Tan, Zhi, Boini, Krishna M., Yang, Tianxin, Zhu, Qing, Wang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850921/ https://www.ncbi.nlm.nih.gov/pubmed/31565858 http://dx.doi.org/10.1111/jcmm.14684 |
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