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In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small‐cell lung cancer

Cancer stem cells (CSCs) play an important role in cancer treatment resistance and disease progression. Identifying an effective anti‐CSC agent may lead to improved disease control. We used CSC‐associated gene signatures to identify drug candidates that may inhibit CSC growth by reversing the CSC ge...

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Detalles Bibliográficos
Autores principales: Huang, Tse‐Hung, Wu, Alexander T. H., Cheng, Tai‐Shan, Lin, Kuan‐Ting, Lai, Chia‐Jou, Hsieh, Hao‐Wen, Chang, Peter Mu‐Hsin, Wu, Cheng‐Wen, Huang, Chi‐Ying F., Chen, Kuan‐Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850923/
https://www.ncbi.nlm.nih.gov/pubmed/31638335
http://dx.doi.org/10.1111/jcmm.14689