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Non‐lethal proteasome inhibition activates pro‐tumorigenic pathways in multiple myeloma cells

Multiple myeloma (MM) is a haematological malignancy being characterized by clonal plasma cell proliferation in the bone marrow. Targeting the proteasome with specific inhibitors (PIs) has been proven a promising therapeutic strategy and PIs have been approved for the treatment of MM and mantle‐cell...

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Detalles Bibliográficos
Autores principales: Skorda, Aikaterini, Sklirou, Aimilia D., Sakellaropoulos, Theodore, Gianniou, Despoina D., Kastritis, Efstathios, Terpos, Evangelos, Tsitsilonis, Ourania E., Florea, Bogdan I., Overkleeft, Herman S., Dimopoulos, Meletios A., Alexopoulos, Leonidas G., Trougakos, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850931/
https://www.ncbi.nlm.nih.gov/pubmed/31568628
http://dx.doi.org/10.1111/jcmm.14653