miR‐200c suppresses stemness and increases cellular sensitivity to trastuzumab in HER2+ breast cancer

Resistance to trastuzumab remains a major obstacle in HER2‐overexpressing breast cancer treatment. miR‐200c is important for many functions in cancer stem cells (CSCs), including tumour recurrence, metastasis and resistance. We hypothesized that miR‐200c contributes to trastuzumab resistance and ste...

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Detalles Bibliográficos
Autores principales: Tang, Hailin, Song, Cailu, Ye, Feng, Gao, Guanfeng, Ou, Xueqi, Zhang, Lijuan, Xie, Xinhua, Xie, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850933/
https://www.ncbi.nlm.nih.gov/pubmed/31599500
http://dx.doi.org/10.1111/jcmm.14681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850933/
https://www.ncbi.nlm.nih.gov/pubmed/31599500
http://dx.doi.org/10.1111/jcmm.14681

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