Asperpyrone A attenuates RANKL‐induced osteoclast formation through inhibiting NFATc1, Ca(2+) signalling and oxidative stress

Imbalance of osteoblast and osteoclast in adult leads to a variety of bone‐related diseases, including osteoporosis. Thus, suppressing the activity of osteoclastic bone resorption becomes the main therapeutic strategy for osteoporosis. Asperpyrone A is a natural compound isolated from Aspergillus ni...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Wang, Chao, Qiu, Heng, Yuan, Yu, Chen, Kai, Cao, Zhen, Xiang Tan, Ren, Tickner, Jennifer, Xu, Jiake, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850946/
https://www.ncbi.nlm.nih.gov/pubmed/31612613
http://dx.doi.org/10.1111/jcmm.14700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850946/
https://www.ncbi.nlm.nih.gov/pubmed/31612613
http://dx.doi.org/10.1111/jcmm.14700

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