Cargando…

Asperpyrone A attenuates RANKL‐induced osteoclast formation through inhibiting NFATc1, Ca(2+) signalling and oxidative stress

Imbalance of osteoblast and osteoclast in adult leads to a variety of bone‐related diseases, including osteoporosis. Thus, suppressing the activity of osteoclastic bone resorption becomes the main therapeutic strategy for osteoporosis. Asperpyrone A is a natural compound isolated from Aspergillus ni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xi, Wang, Chao, Qiu, Heng, Yuan, Yu, Chen, Kai, Cao, Zhen, Xiang Tan, Ren, Tickner, Jennifer, Xu, Jiake, Zou, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850946/ https://www.ncbi.nlm.nih.gov/pubmed/31612613 http://dx.doi.org/10.1111/jcmm.14700

Ejemplares similares

Fumitremorgin C Attenuates Osteoclast Formation and Function via Suppressing RANKL-Induced Signaling Pathways
por: Yuan, Yu, et al.
Publicado: (2020)

Inhibitory Effects of Rhaponticin on Osteoclast Formation and Resorption by Targeting RANKL-Induced NFATc1 and ROS Activity
por: He, Jianbo, et al.
Publicado: (2021)

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities
por: Liu, Yuhao, et al.
Publicado: (2019)

Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways
por: Zhou, Lin, et al.
Publicado: (2015)

Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract of Euphorbia Lathyris L
por: Kang, Ju-Hee, et al.
Publicado: (2016)

Fangchinoline protects against bone loss in OVX mice via inhibiting osteoclast formation, bone resorption and RANKL-induced signaling
por: Zhou, Lin, et al.
Publicado: (2020)

PKC-δ deficiency in B cells displays osteopenia accompanied with upregulation of RANKL expression and osteoclast–osteoblast uncoupling
por: Li, Shangfu, et al.
Publicado: (2020)

Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways
por: Hong, Guoju, et al.
Publicado: (2020)

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation
por: Liu, Qian, et al.
Publicado: (2016)

ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption
por: Qiu, Heng, et al.
Publicado: (2023)

Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation
por: Hu, Zi’ang, et al.
Publicado: (2018)

Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL‐stimulated NFATc1 activity
por: Liu, Yuhao, et al.
Publicado: (2020)

Cycloastragenol Attenuates Osteoclastogenesis and Bone Loss by Targeting RANKL-Induced Nrf2/Keap1/ARE, NF-κB, Calcium, and NFATc1 Pathways
por: Wang, Gang, et al.
Publicado: (2022)

Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1
por: Ibáñez, Lidia, et al.
Publicado: (2022)

Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis via suppressing NFATc1 activation
por: Wang, Lu, et al.
Publicado: (2019)

Bajijiasu Abrogates Osteoclast Differentiation via the Suppression of RANKL Signaling Pathways through NF-κB and NFAT
por: Hong, Guoju, et al.
Publicado: (2017)

NADPH oxidase gp91(phox) contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1
por: Kang, In Soon, et al.
Publicado: (2016)

Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity
por: Liu, Yuhao, et al.
Publicado: (2020)

ThPOK Inhibits Osteoclast Formation Via NFATc1 Transcription and Function
por: Zou, Wei, et al.
Publicado: (2022)

Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-κB Activation, and IκBα Degradation
por: Qin, Shengnan, et al.
Publicado: (2015)

The Effects of Aronia melanocarpa ‘Viking’ Extracts in Attenuating RANKL-Induced Osteoclastic Differentiation by Inhibiting ROS Generation and c-FOS/NFATc1 Signaling
por: Ghosh, Mithun, et al.
Publicado: (2018)

Sinomenine Suppresses Osteoclast Formation and Mycobacterium tuberculosis H37Ra-Induced Bone Loss by Modulating RANKL Signaling Pathways
por: Li, Xiaojuan, et al.
Publicado: (2013)

Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression
por: Kim, Eun-Jung, et al.
Publicado: (2018)

Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation
por: Wu, Lili, et al.
Publicado: (2019)

IRF2 enhances RANKL-induced osteoclast differentiation via regulating NF-κB/NFATc1 signaling
por: Kim, Inyoung, et al.
Publicado: (2021)

NCX1 disturbs calcium homeostasis and promotes RANKL-induced osteoclast differentiation by regulating JNK/c-Fos/NFATc1 signaling pathway in multiple myeloma
por: Li, Tingting, et al.
Publicado: (2022)

Regulation of NFATc1 in Osteoclast Differentiation
por: Kim, Jung Ha, et al.
Publicado: (2014)

Betulin Suppresses Osteoclast Formation via Down-Regulating NFATc1
por: Kim, Kwang-Jin, et al.
Publicado: (2018)

Oat Seedlings Extract Inhibits RANKL-Induced c-Fos/NFATc1 Transcription Factors in the Early Stage of Osteoclast Differentiation
por: Yang, Ji Yeong, et al.
Publicado: (2022)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis
por: Jin, Haiming, et al.
Publicado: (2019)

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption
por: Zhu, Sipin, et al.
Publicado: (2016)

Serum amyloid A inhibits RANKL-induced osteoclast formation
por: Oh, Eunseo, et al.
Publicado: (2015)

The effects of vasoactive intestinal peptide on RANKL-induced osteoclast formation
por: Qu, Hongyi, et al.
Publicado: (2021)

Zinc inhibits osteoclast differentiation by suppression of Ca(2+)-Calcineurin-NFATc1 signaling pathway
por: Park, Kwang Hwan, et al.
Publicado: (2013)

Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1
por: Song, Min-Kyoung, et al.
Publicado: (2015)

TNF-α Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation
por: Marahleh, Aseel, et al.
Publicado: (2019)

Evodiamine inhibits RANKL‐induced osteoclastogenesis and prevents ovariectomy‐induced bone loss in mice
por: Jin, Haiming, et al.
Publicado: (2018)

Madecassoside inhibits estrogen deficiency‐induced osteoporosis by suppressing RANKL‐induced osteoclastogenesis
por: Wang, Qingqing, et al.
Publicado: (2018)

The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation
por: Liu, Fei-Lan, et al.
Publicado: (2017)

MicroRNA-26a Regulates RANKL-Induced Osteoclast Formation
por: Kim, Kabsun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kp4iff5sul59rnsb168a83dlq0