Simvastatin preparations promote PDGF‐BB secretion to repair LPS‐induced endothelial injury through the PDGFRβ/PI3K/Akt/IQGAP1 signalling pathway

Endothelial barrier dysfunction is a critical pathophysiological process of sepsis. Impaired endothelial cell migration is one of the main reasons for endothelial dysfunction. Statins may have a protective effect on endothelial barrier function. However, the effect and mechanism of statins on lipopo...

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Detalles Bibliográficos
Autores principales: Zheng, Xia, Zhang, Wang, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850957/
https://www.ncbi.nlm.nih.gov/pubmed/31576676
http://dx.doi.org/10.1111/jcmm.14709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850957/
https://www.ncbi.nlm.nih.gov/pubmed/31576676
http://dx.doi.org/10.1111/jcmm.14709

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