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Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype

Mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease (PD). The LRRK2 physiological and pathological function is still debated. However, different experimental evidence based on LRRK2 cellular localization and LRRK2 protein interactors sugges...

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Detalles Bibliográficos
Autores principales: Rassu, Mauro, Biosa, Alice, Galioto, Manuela, Fais, Milena, Sini, Paola, Greggio, Elisa, Piccoli, Giovanni, Crosio, Claudia, Iaccarino, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850958/
https://www.ncbi.nlm.nih.gov/pubmed/31560168
http://dx.doi.org/10.1111/jcmm.14674