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Large neutral amino acid status in association with P:T ratio and diet in adult and pediatric patients with phenylketonuria

BACKGROUND: Intake of large neutral amino acids (LNAA) may inhibit phenylalanine (PHE) transport across the blood brain barrier and assist with blood PHE control in patients with phenylketonuria (PKU). We evaluated the interrelationship between LNAA in plasma and diet on Phe:Tyr (P:T) ratio in patie...

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Detalles Bibliográficos
Autores principales: Douglas, Teresa D., Nucci, Anita M., Berry, Ann M., Henes, Sarah T., Singh, Rani H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850973/
https://www.ncbi.nlm.nih.gov/pubmed/31741827
http://dx.doi.org/10.1002/jmd2.12076