Cargando…

G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells

G protein-coupled receptor kinase 2 (GRK2) is an important protein involved in β-adrenergic receptor desensitization. In addition, studies have shown GRK2 can modulate different metabolic processes in the cell. For instance, GRK2 has been recently shown to promote mitochondrial biogenesis and increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Manfredi, Leandro Henrique, Ang, Joshur, Peker, Nesibe, Dagda, Ruben K., McFarlane, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850988/
https://www.ncbi.nlm.nih.gov/pubmed/31268780
http://dx.doi.org/10.1152/ajpcell.00516.2018