G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells

G protein-coupled receptor kinase 2 (GRK2) is an important protein involved in β-adrenergic receptor desensitization. In addition, studies have shown GRK2 can modulate different metabolic processes in the cell. For instance, GRK2 has been recently shown to promote mitochondrial biogenesis and increa...

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Detalles Bibliográficos
Autores principales: Manfredi, Leandro Henrique, Ang, Joshur, Peker, Nesibe, Dagda, Ruben K., McFarlane, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850988/
https://www.ncbi.nlm.nih.gov/pubmed/31268780
http://dx.doi.org/10.1152/ajpcell.00516.2018

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