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Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression

Viral vectors are efficient gene delivery systems, although most of these vectors still present limitations to their practical use, such as achieving only transient transgene expression and a risk of insertional mutations. We have recently developed an RNA virus-based episomal vector (REVec), based...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yusuke, Tomonaga, Keizo, Honda, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851019/
https://www.ncbi.nlm.nih.gov/pubmed/31781052
http://dx.doi.org/10.3389/fmicb.2019.02485