A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli

Monoclonal antibodies (mABs) are of great biopharmaceutical importance for the diagnosis and treatment of diseases. However, their production in mammalian expression hosts usually requires extensive production times and is expensive. Escherichia coli has become a new platform for production of funct...

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Detalles Bibliográficos
Autores principales: Petrus, Marloes L. C., Kiefer, Lukas A., Puri, Pranav, Heemskerk, Evert, Seaman, Michael S., Barouch, Dan H., Arias, Sagrario, van Wezel, Gilles P., Havenga, Menzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851033/
https://www.ncbi.nlm.nih.gov/pubmed/31641814
http://dx.doi.org/10.1007/s00253-019-10145-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851033/
https://www.ncbi.nlm.nih.gov/pubmed/31641814
http://dx.doi.org/10.1007/s00253-019-10145-1

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