STS-NLSP: A Network-Based Label Space Partition Method for Predicting the Specificity of Membrane Transporter Substrates Using a Hybrid Feature of Structural and Semantic Similarity

Membrane transport proteins play crucial roles in the pharmacokinetics of substrate drugs, the drug resistance in cancer and are vital to the process of drug discovery, development and anti-cancer therapeutics. However, experimental methods to profile a substrate drug against a panel of transporters...

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Detalles Bibliográficos
Autores principales: Wang, Xiangeng, Zhu, Xiaolei, Ye, Mingzhi, Wang, Yanjing, Li, Cheng-Dong, Xiong, Yi, Wei, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851049/
https://www.ncbi.nlm.nih.gov/pubmed/31781551
http://dx.doi.org/10.3389/fbioe.2019.00306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851049/
https://www.ncbi.nlm.nih.gov/pubmed/31781551
http://dx.doi.org/10.3389/fbioe.2019.00306

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