Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

The mouse is the most widely used animal model for influenza virus research. However, the susceptibility of mice to seasonal influenza virus depends on the strain of mouse and on the strain of the influenza virus. Seasonal A/H3N2 influenza viruses do not replicate well in mice and therefore they nee...

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Detalles Bibliográficos
Autores principales: Baz, Mariana, M’hamdi, Zeineb, Carbonneau, Julie, Lavigne, Sophie, Couture, Christian, Abed, Yacine, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851088/
https://www.ncbi.nlm.nih.gov/pubmed/31719554
http://dx.doi.org/10.1038/s41598-019-51877-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851088/
https://www.ncbi.nlm.nih.gov/pubmed/31719554
http://dx.doi.org/10.1038/s41598-019-51877-4

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