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Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus
The mouse is the most widely used animal model for influenza virus research. However, the susceptibility of mice to seasonal influenza virus depends on the strain of mouse and on the strain of the influenza virus. Seasonal A/H3N2 influenza viruses do not replicate well in mice and therefore they nee...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851088/ https://www.ncbi.nlm.nih.gov/pubmed/31719554 http://dx.doi.org/10.1038/s41598-019-51877-4 |