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Integrative analysis of clinical and bioinformatics databases to identify anticancer properties of digoxin
Cardiac glycosides, such as digoxin, inhibit Na(+)/K(+)-ATPases and cause secondary activation of Na(+)/Ca(2+) exchangers. Preclinical investigations have suggested that digoxin may have anticancer properties. In order to clarify the functional mechanisms of digoxin in cancer, we performed an integr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851125/ https://www.ncbi.nlm.nih.gov/pubmed/31719612 http://dx.doi.org/10.1038/s41598-019-53392-y |