Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room

Alpha-synuclein is an intrinsically disordered, highly dynamic protein that pathogenically aggregates into inclusion structures called Lewy bodies, in several neurogenerative diseases termed synucleinopathies. Despite its importance for understanding disease, the oligomerization status of alpha-synu...

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Detalles Bibliográficos
Autores principales: Killinger, Bryan A., Melki, Ronald, Brundin, Patrik, Kordower, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851126/
https://www.ncbi.nlm.nih.gov/pubmed/31728405
http://dx.doi.org/10.1038/s41531-019-0095-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851126/
https://www.ncbi.nlm.nih.gov/pubmed/31728405
http://dx.doi.org/10.1038/s41531-019-0095-3

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