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Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging

Glioblastoma multiforme (GBM) is one of the most aggressive human tumors with poor survival rates. The current standard treatment includes chemotherapy with temozolomide (TMZ), but acquisition of resistance is a persistent clinical problem limiting the successful treatment of GBM. The purpose of our...

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Detalles Bibliográficos
Autores principales: Cho, Hye Rim, Kumari, Nisha, Thakur, Nishant, Vu, Hien Thi, Kim, Hyeonjin, Choi, Seung Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851184/
https://www.ncbi.nlm.nih.gov/pubmed/31719653
http://dx.doi.org/10.1038/s41598-019-53147-9