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A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein
Parkinson’s disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuronal loss that initiates in the substantia nigra pars compacta and by the formation of intracellular inclusions mainly constituted by aberrant α-synuclein (α-syn) deposits known as Lewy...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851186/ https://www.ncbi.nlm.nih.gov/pubmed/31719530 http://dx.doi.org/10.1038/s41419-019-2092-1 |