Activation of PXR by alantolactone ameliorates DSS-induced experimental colitis via suppressing NF-κB signaling pathway

Alantolactone (ALA) is a sesquiterpene lactone with potent anti-inflammatory activity. However, the effect of ALA on intestinal inflammation remains largely unknown. The present study demonstrated that ALA significantly ameliorated the clinical symptoms of dextran sulfate sodium (DSS)-induced mice c...

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Detalles Bibliográficos
Autores principales: Ren, Yijing, Yue, Bei, Ren, Gaiyan, Yu, Zhilun, Luo, Xiaoping, Sun, Aning, Zhang, Jingjing, Han, Mengqing, Wang, Zhengtao, Dou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851188/
https://www.ncbi.nlm.nih.gov/pubmed/31719637
http://dx.doi.org/10.1038/s41598-019-53305-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851188/
https://www.ncbi.nlm.nih.gov/pubmed/31719637
http://dx.doi.org/10.1038/s41598-019-53305-z

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