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Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer
Zinc is vital for the structure and function of ~3000 human proteins and hence plays key physiological roles. Consequently, impaired zinc homeostasis is associated with various human diseases including cancer. Intracellular zinc levels are tightly regulated by two families of zinc transporters: ZIPs...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851190/ https://www.ncbi.nlm.nih.gov/pubmed/31728210 http://dx.doi.org/10.1038/s41420-019-0224-0 |