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Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer

Zinc is vital for the structure and function of ~3000 human proteins and hence plays key physiological roles. Consequently, impaired zinc homeostasis is associated with various human diseases including cancer. Intracellular zinc levels are tightly regulated by two families of zinc transporters: ZIPs...

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Detalles Bibliográficos
Autores principales: Lehvy, Adrian Israel, Horev, Guy, Golan, Yarden, Glaser, Fabian, Shammai, Yael, Assaraf, Yehuda Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851190/
https://www.ncbi.nlm.nih.gov/pubmed/31728210
http://dx.doi.org/10.1038/s41420-019-0224-0