Salt-free fractionation of complex isomeric mixtures of glycosaminoglycan oligosaccharides compatible with ESI-MS and microarray analysis

Heparin and heparan sulfate (Hp/HS) are linear complex glycosaminoglycans which are involved in diverse biological processes. The structural complexity brings difficulties in separation, making the study of structure-function relationships challenging. Here we present a separation method for Hp/HS o...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Joshi, Apoorva, Chopra, Pradeep, Liu, Lin, Boons, Geert-Jan, Sharp, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851191/
https://www.ncbi.nlm.nih.gov/pubmed/31719635
http://dx.doi.org/10.1038/s41598-019-53070-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851191/
https://www.ncbi.nlm.nih.gov/pubmed/31719635
http://dx.doi.org/10.1038/s41598-019-53070-z

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