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Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure

Microglia are highly plastic immune cells which exist in a continuum of activation states. By shaping the function of oligodendrocyte precursor cells (OPCs), the brain cells which differentiate to myelin-forming cells, microglia participate in both myelin injury and remyelination during multiple scl...

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Detalles Bibliográficos
Autores principales: Lombardi, Marta, Parolisi, Roberta, Scaroni, Federica, Bonfanti, Elisabetta, Gualerzi, Alice, Gabrielli, Martina, Kerlero de Rosbo, Nicole, Uccelli, Antonio, Giussani, Paola, Viani, Paola, Garlanda, Cecilia, Abbracchio, Maria P., Chaabane, Linda, Buffo, Annalisa, Fumagalli, Marta, Verderio, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851224/
https://www.ncbi.nlm.nih.gov/pubmed/31363836
http://dx.doi.org/10.1007/s00401-019-02049-1