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The dystroglycan receptor maintains glioma stem cells in the vascular niche

Glioblastomas (GBMs) are malignant central nervous system (CNS) neoplasms with a very poor prognosis. They display cellular hierarchies containing self-renewing tumourigenic glioma stem cells (GSCs) in a complex heterogeneous microenvironment. One proposed GSC niche is the extracellular matrix (ECM)...

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Detalles Bibliográficos
Autores principales: Day, Bryan W., Lathia, Justin D., Bruce, Zara C., D’Souza, Rochelle C. J., Baumgartner, Ulrich, Ensbey, Kathleen S., Lim, Yi Chieh, Stringer, Brett W., Akgül, Seçkin, Offenhäuser, Carolin, Li, Yuchen, Jamieson, Paul R., Smith, Fiona M., Jurd, Courtney L. R., Robertson, Thomas, Inglis, Po-Ling, Lwin, Zarnie, Jeffree, Rosalind L., Johns, Terrance G., Bhat, Krishna P. L., Rich, Jeremy N., Campbell, Kevin P., Boyd, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851226/
https://www.ncbi.nlm.nih.gov/pubmed/31463571
http://dx.doi.org/10.1007/s00401-019-02069-x