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Delayed Azithromycin Treatment Improves Recovery After Mouse Spinal Cord Injury

After spinal cord injury (SCI), macrophages infiltrate into the lesion and can adopt a wide spectrum of activation states. However, the pro-inflammatory, pathological macrophage activation state predominates and contributes to progressive neurodegeneration. Azithromycin (AZM), an FDA approved macrol...

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Detalles Bibliográficos
Autores principales: Kopper, Timothy J., McFarlane, Katelyn E., Bailey, William M., Orr, Michael B., Zhang, Bei, Gensel, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851268/
https://www.ncbi.nlm.nih.gov/pubmed/31780896
http://dx.doi.org/10.3389/fncel.2019.00490