Cargando…

Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection

Staphylococcus aureus is a deadly pathogen that causes fatal diseases in humans. During infection, S. aureus secretes nuclease (Nuc) and adenosine synthase A (AdsA) to generate cytotoxic deoxyadenosine (dAdo) from neutrophil extracellular traps which triggers noninflammatory apoptosis in macrophages...

Descripción completa

Detalles Bibliográficos
Autores principales: Winstel, Volker, Schneewind, Olaf, Missiakas, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851280/
https://www.ncbi.nlm.nih.gov/pubmed/31719177
http://dx.doi.org/10.1128/mBio.02270-19