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Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection
Staphylococcus aureus is a deadly pathogen that causes fatal diseases in humans. During infection, S. aureus secretes nuclease (Nuc) and adenosine synthase A (AdsA) to generate cytotoxic deoxyadenosine (dAdo) from neutrophil extracellular traps which triggers noninflammatory apoptosis in macrophages...
Autores principales: | Winstel, Volker, Schneewind, Olaf, Missiakas, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851280/ https://www.ncbi.nlm.nih.gov/pubmed/31719177 http://dx.doi.org/10.1128/mBio.02270-19 |
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