Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

The rapid spread of multidrug-resistant strains has created a pressing need for new drug regimens to treat tuberculosis (TB), which kills 1.8 million people each year. Identifying new regimens has been challenging due to the slow growth of the pathogen Mycobacterium tuberculosis (MTB), coupled with...

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Detalles Bibliográficos
Autores principales: Ma, Shuyi, Jaipalli, Suraj, Larkins-Ford, Jonah, Lohmiller, Jenny, Aldridge, Bree B., Sherman, David R., Chandrasekaran, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851285/
https://www.ncbi.nlm.nih.gov/pubmed/31719182
http://dx.doi.org/10.1128/mBio.02627-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851285/
https://www.ncbi.nlm.nih.gov/pubmed/31719182
http://dx.doi.org/10.1128/mBio.02627-19

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