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Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis
The rapid spread of multidrug-resistant strains has created a pressing need for new drug regimens to treat tuberculosis (TB), which kills 1.8 million people each year. Identifying new regimens has been challenging due to the slow growth of the pathogen Mycobacterium tuberculosis (MTB), coupled with...
Autores principales: | Ma, Shuyi, Jaipalli, Suraj, Larkins-Ford, Jonah, Lohmiller, Jenny, Aldridge, Bree B., Sherman, David R., Chandrasekaran, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851285/ https://www.ncbi.nlm.nih.gov/pubmed/31719182 http://dx.doi.org/10.1128/mBio.02627-19 |
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