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TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function

Macrophages are a reservoir for latent human immunodeficiency type 1 (HIV) infection and a barrier to HIV eradication. In contrast to CD4(+) T cells, macrophages are resistant to the cytopathic effects of acute HIV infection. Emerging data suggest a role for TREM1 (triggering receptor expressed on m...

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Detalles Bibliográficos
Autores principales: Campbell, Grant R., To, Rachel K., Spector, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851287/
https://www.ncbi.nlm.nih.gov/pubmed/31719184
http://dx.doi.org/10.1128/mBio.02638-19