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Design and development of stapled transmembrane peptides that disrupt the activity of G-protein–coupled receptor oligomers
Membrane proteins can associate into larger complexes. Examples include receptor tyrosine complexes, ion channels, transporters, and G protein–coupled receptors (GPCRs). For the latter, there is abundant evidence indicating that GPCRs assemble into complexes, through both homo- and heterodimerizatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851324/ https://www.ncbi.nlm.nih.gov/pubmed/31467080 http://dx.doi.org/10.1074/jbc.RA119.009160 |