Single-molecule analysis reveals rotational substeps and chemo-mechanical coupling scheme of Enterococcus hirae V(1)-ATPase

V(1)-ATPase (V(1)), the catalytic domain of an ion-pumping V-ATPase, is a molecular motor that converts ATP hydrolysis–derived chemical energy into rotation. Here, using a gold nanoparticle probe, we directly observed rotation of V(1) from the pathogen Enterococcus hirae (EhV(1)). We found that 120°...

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Detalles Bibliográficos
Autores principales: Iida, Tatsuya, Minagawa, Yoshihiro, Ueno, Hiroshi, Kawai, Fumihiro, Murata, Takeshi, Iino, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851342/
https://www.ncbi.nlm.nih.gov/pubmed/31519751
http://dx.doi.org/10.1074/jbc.RA119.008947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851342/
https://www.ncbi.nlm.nih.gov/pubmed/31519751
http://dx.doi.org/10.1074/jbc.RA119.008947

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